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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA2
All Species:
13.94
Human Site:
T740
Identified Species:
25.56
UniProt:
Q9BZC7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZC7
NP_001597
2435
269873
T740
R
L
K
E
V
M
K
T
M
G
L
N
N
A
V
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
Q690
Y
L
Q
D
M
V
E
Q
G
I
T
R
S
Q
V
Rhesus Macaque
Macaca mulatta
XP_001117819
2476
273629
T767
R
L
K
E
V
M
K
T
M
G
L
N
N
A
V
Dog
Lupus familis
XP_537788
2395
264756
T740
R
L
K
E
V
M
K
T
M
G
L
N
N
A
V
Cat
Felis silvestris
Mouse
Mus musculus
P41234
2434
270490
M740
L
K
E
V
M
K
T
M
G
L
N
N
A
V
H
Rat
Rattus norvegicus
Q9ESR9
2434
270910
T740
R
L
K
E
V
M
K
T
M
G
L
N
N
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
I654
L
F
M
T
L
A
W
I
Y
S
V
A
V
I
I
Chicken
Gallus gallus
XP_422330
2276
256293
Y664
F
M
V
L
A
W
I
Y
S
V
S
M
T
V
K
Frog
Xenopus laevis
NP_001089022
2363
267334
N688
R
L
K
E
T
M
K
N
M
G
V
T
N
D
V
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
V656
T
L
A
W
M
Y
S
V
A
I
I
I
K
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
G92
L
R
S
D
V
V
V
G
Y
T
S
K
D
A
A
Sea Urchin
Strong. purpuratus
XP_798273
1913
213253
I301
I
R
N
H
L
D
V
I
D
N
A
A
C
A
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
D269
P
T
R
E
Y
T
D
D
E
F
Q
S
I
V
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
96
82.2
N.A.
91
92.9
N.A.
39.1
35.7
36.5
37.7
N.A.
N.A.
N.A.
23.7
41.7
Protein Similarity:
100
52
96.6
86.1
N.A.
93.2
94.9
N.A.
55.7
53.5
54.7
54.5
N.A.
N.A.
N.A.
39
54.4
P-Site Identity:
100
13.3
100
100
N.A.
6.6
100
N.A.
0
0
66.6
13.3
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
53.3
100
100
N.A.
20
100
N.A.
20
6.6
73.3
26.6
N.A.
N.A.
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
0
0
8
0
8
16
8
47
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
16
0
8
8
8
8
0
0
0
8
8
0
% D
% Glu:
0
0
8
47
0
0
8
0
8
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
16
39
0
0
0
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
0
0
8
16
0
16
8
8
8
8
8
% I
% Lys:
0
8
39
0
0
8
39
0
0
0
0
8
8
0
16
% K
% Leu:
24
54
0
8
16
0
0
0
0
8
31
0
0
0
0
% L
% Met:
0
8
8
0
24
39
0
8
39
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
8
8
39
39
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
8
0
0
8
0
% Q
% Arg:
39
16
8
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
0
8
8
16
8
8
0
0
% S
% Thr:
8
8
0
8
8
8
8
31
0
8
8
8
8
0
0
% T
% Val:
0
0
8
8
39
16
16
8
0
8
16
0
8
24
54
% V
% Trp:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
8
8
0
8
16
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _